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Rheumatoid Arthritis, Psoriatic arthritis,Ulcerati

Our range of products include tofacitinib.

Tofacitinib

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Tofacitinib
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Approx. Rs 27,000 / BottleGet Latest Price

Product Details:
Minimum Order Quantity1 Bottle
Dose/Strength5MG
Drug NameXELJANZ
Dosage FormTablet
Active IngredientTofacitinib
1 Box Contain Bottle60 TABLET
ConditionFINISHED GOOD
Delivery Type5-7 DAYS

Tofacitinib, sold under the brand Xeljanz among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

It is an inhibitor of the enzyme janus kinase 1 (JAK1) and janus kinase 3 (JAK , which means that it interferes with the JAK-STAT signaling pathway, which transmits extracellular information into the cell nucleus, influencing DNA transcription.

In a mouse model of established arthritis, tofacitinib rapidly improved disease by inhibiting the production of inflammatory mediators and suppressing STAT1-dependent genes in joint tissue. This efficacy in this disease model correlated with the inhibition of both JAK1 and 3 signaling pathways, suggesting that tofacitinib may exert therapeutic benefit via pathways that are not exclusive to inhibition of JAK3.


Additional Information:

  • Delivery Time: 5-7 DAYS
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