Approx. Rs 27,000 / BottleGet Latest PriceProduct Details:
|Minimum Order Quantity||1 Bottle|
|1 Box Contain Bottle||60 TABLET|
|Delivery Type||5-7 DAYS|
It is an inhibitor of the enzyme janus kinase 1 (JAK1) and janus kinase 3 (JAK , which means that it interferes with the JAK-STAT signaling pathway, which transmits extracellular information into the cell nucleus, influencing DNA transcription.
In a mouse model of established arthritis, tofacitinib rapidly improved disease by inhibiting the production of inflammatory mediators and suppressing STAT1-dependent genes in joint tissue. This efficacy in this disease model correlated with the inhibition of both JAK1 and 3 signaling pathways, suggesting that tofacitinib may exert therapeutic benefit via pathways that are not exclusive to inhibition of JAK3.
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